Liver transplant in Turkey

Liver Transplantation in Turkey
Liver Transplantation in Turkey:
Liver transplantation is the only and final treatment option for acute liver failure, end-stage liver disease (cirrhosis), irreversible liver damage, and certain liver cancers. Liver transplant is the most recognized treatment worldwide for patients with liver failure, offering high success rates. Every day, many people globally are given a new chance at life through liver transplants, including in Turkey, which offers high-quality procedures at more affordable prices compared to other countries.
What Are the Functions of the Liver?
The liver is the largest organ in the body, weighing between 1.4 and 1.7 kg. It is soft, pinkish-brown, and triangular in shape.
The primary functions of the liver include:
- Converting food into nutrients usable by the body (e.g., converting starch into sugar, producing bile to digest fats).
- Producing clotting factors, enzymes, and other proteins.
- Storing energy sources such as iron, vitamins, fats, and sugars.
- Removing toxic substances like drugs and alcohol that can harm the body.
The Liver’s Regenerative Ability
More than half of a donor’s liver can be removed for transplantation without impairing liver function or causing significant damage. The liver is the only organ in the body capable of regenerating itself after partial removal. Life after a liver transplant is not significantly impacted, as the liver regrows to its normal size within 7 days to 3 months. Most regeneration occurs within the first week, allowing half of the donor’s liver to be successfully transplanted to a patient with liver failure.
Liver Diseases Requiring Transplantation
Liver damage can occur due to various diseases. When the liver’s natural structure is damaged and replaced by nodules and fibrotic tissues over time, it is classified as cirrhosis. The only treatment for this irreversible liver damage is transplantation. Cirrhosis remains one of the main conditions necessitating liver transplants worldwide and in Turkey. Transplants are also used for certain congenital diseases and liver tumors.
While alcohol consumption is the leading cause of liver disease in Western Europe and North America, viral hepatitis is a major public health issue in other regions and the primary cause of cirrhosis in Turkey. With advanced methods and modern techniques, liver transplantation in Turkey has achieved a high success rate.
Symptoms of End-Stage Liver Failure
Patients with advanced liver failure may experience the following symptoms:
- Mild fever
- Nausea and vomiting
- Edema
- Spontaneous bleeding from the nose or gums
- Redness and bruising on the body
- Loss of appetite
- Muscle cramps
- Weakness and fatigue
- Itching
- Breast enlargement (gynecomastia) in men
- Hair thinning and irregular distribution
- Changes in sexual behavior
- Weight fluctuations
- Low blood pressure
- Slowed movements and speech
Types of Liver Transplants in Turkey
Liver transplantation can be performed through two methods:
- Deceased Donor Liver Transplant:
This method involves organ donation from individuals who are brain dead. The donated liver must be removed under appropriate conditions, preserved in special solutions, and transplanted within 24 hours. - Living Donor Liver Transplant:
In this procedure, a healthy volunteer donates a part of their liver. The donor must be a relative within four degrees of kinship or pass ethics committee approval if there is no family relationship. The process ensures that both the donor and recipient have suitable liver anatomy, vessels, and bile ducts.
Eligibility for Liver Donation in Turkey
To become a liver donor, a person must meet the following criteria:
- Be at least 18 years old.
- Be younger than 60, depending on their and the recipient’s health.
- Donate voluntarily.
- Share a blood type match with the recipient (same type or universal group).
- Have no history of systemic diseases or chronic hepatitis.
Aftercare and Follow-up
Following the transplant, patients require careful monitoring to ensure recovery. Some key aspects include:
- Wound Care: Keep the surgical wound clean using antiseptic soap and report any redness or swelling.
- Monitoring Bile Drainage Stents: Clean the area around the stent to prevent infection and consult a doctor if any issues arise.
- Temperature Monitoring: Fever may indicate infection or rejection; contact a transplant team if it exceeds 38°C.
Liver Transplant Success Rates in Turkey
Turkey has become internationally recognized for liver transplantation, with success rates ranging between 90-95% due to:
- Careful donor and recipient matching.
- Thorough medical evaluation and preparation.
- Expertise of surgeons and medical teams.
- High-quality post-operative care and monitoring.
Liver Transplant Costs in Turkey
The cost of a liver transplant in Turkey typically ranges between $45,000 and $70,000, depending on factors such as:
- Hospital and medical team qualifications.
- Follow-up care requirements.
- The patient’s overall health condition.
Turkey remains a popular destination for medical tourism, offering high-quality healthcare at more affordable prices compared to many Western countries.
For precise information and personalized cost estimates, contact us today to explore your options for liver transplantation in Turkey.
The most common questions about liver transplantation in Turkey
What are the causes of liver failure?
الوقت المتطلب للقراءة 9 دقيقة
The liver has the ability to overcome the damage it has caused after many diseases by replenishing itself. However, in some cases, this capacity may not be sufficient and the liver may be irreversibly damaged. most of them are from; While it may be the result of genetic / family / hereditary abnormalities, especially in children, the causes are different in adults. The most common cause in infants and children is the absence of congenital bile ducts (biliary atresia), followed by other metabolic and hereditary diseases (PFIC: progressive familial cholestasis within the liver, Wilson’s disease, and hepatoblastoma: childhood liver cancer, deficiency of a genetic enzyme) .
The most common cause in adults is the hepatitis B virus (HBV). Hepatitis C virus (HCV) is more common in the Western world. Moreover, alcohol can be an autoimmune disease (autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis), Wilson’s disease, Chiari-Bodhi syndrome, and coding cirrhosis (an unknown cause). Liver cancer development based on any chronic liver disease is also an important reason for transplantation.
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When should a liver transplant be done?
الوقت المتطلب للقراءة 9 دقيقة
In cases of acute liver failure, the patient must be transplanted urgently.
In cases of chronic liver failure called long-term; Patients with end-stage hepatic insufficiency should be given the opportunity for transplantation under constant doctor’s follow-up, after completion of various imaging and biochemical examinations, according to internationally defined criteria. It should not be forgotten that one of the most important steps that increase the success rate of liver transplantation is “not to delay”.
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What are the advantages of liver transplantation?
الوقت المتطلب للقراءة 9 دقيقة
Organ Transplantation
Today, organ transplantation is accepted as a routine, advanced, and effective treatment method applied for many chronic organ diseases. Since there is no dialysis-like support system for liver failure, as there is for kidney failure, patients with liver failure face life-threatening conditions.
A life-saving process made possible through the transplantation of a vital organ like the liver opens the door to a new beginning, and life after liver transplantation becomes “healthy” for our patients. Patients with a survival rate of 10% or less without a liver transplant have a 90% chance of survival following a successful liver transplant.
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Is tissue compatibility necessary for liver transplantation?
الوقت المتطلب للقراءة 9 دقيقة
No. Blood type compatibility is sufficient.
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What are the requirements for a live liver transplant?
الوقت المتطلب للقراءة 9 دقيقة
The mother, father, brother, husband or other relatives and relatives must volunteer. ought to
All checks on this volunteer show that it is okay for a person to give a piece of his liver. These tests are two-way:
first one; Performing checks on all systems to prevent any harm to the organ donor. All organs such as the heart, lungs, digestive system and mental state.
Recent liver exams. In these examinations, all structural features of the liver, arteries, veins, and bile ducts are examined.
If all the checks are appropriate, it is decided that there is no harm in donating the volunteer’s organs. It is usually necessary to take the left side of the donor liver for young children, and the right half of the donor liver for adults or older patients.
The minimum age for liver donation is 18 and the maximum is 50 (60) years. Although there is no certainty about this issue, issues that arise at age 50 and over may prevent this process can be an upper limit of 50 or 60 depending on the status of the sender and the receiver.
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How much liver is taken from a living donor?
الوقت المتطلب للقراءة 9 دقيقة
For young children, it is usually necessary to take the small left side (25%) of the donor’s liver, and for adult patients, the right half (60%) or the left half (40%) of the donor’s liver often needs to be taken.
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How long does live donor surgery take?
الوقت المتطلب للقراءة 9 دقيقة
The liver transplant surgery in Turkey with a living donor takes between 8-18 hours. The duration of the donor surgery is 4-6 hours.
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How is living donor surgery performed?
الوقت المتطلب للقراءة 9 دقيقة
In this surgery, two teams that remove the liver and transplant the liver usually work together and at the same time. The portion of the liver taken from proximal is placed in place of the patient’s liver, which is removed by protecting the patient’s main abdominal vein (the vena cava). It is a more difficult technique than cadaveric surgery as a surgical method. It requires a bigger team. At least 4 surgeons, 6 nurses and an anesthesiologist work during the operation. In addition, the microsurgery and ultrasound examinations performed during surgery are also required to suture the very small artery.
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How long will a living donor stay in intensive care after surgery?
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Although it varies according to transplant centers, the average duration of intensive care is one day.
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Will a living donor develop liver disease in the future?
الوقت المتطلب للقراءة 9 دقيقة
There are no such risks for long-term donors. The liver is the only organ in the body that can regenerate itself (regenerate), and the organ regains its previous size within 3 months for people whose livers have been removed for any reason. There may be a loss of the donor due to problems related to the period of the operation, but for donors (donors) who are adequately examined before surgery in centers with experience, this risk is 0.5%. In the long term, problems with the donor are not expected. The remaining portion of the liver is sufficient for a healthy individual without endangering his life. The liver reaches its previous size in about 3 months, but the fastest growth occurs within the first 10 days after surgery.
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Can a living donor return to work after surgery?
الوقت المتطلب للقراءة 9 دقيقة
It is very normal to feel tired in the first three months after surgery due to increased energy and need while the liver reaches its previous size. For this reason, those who work in physical activity-based jobs, especially in hard work areas, can return to these jobs within 5-6 months at the earliest. Those with similar light duty and office jobs can return to these jobs within 3-4 months.
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Is the remaining liver sufficient for a living donor to continue life?
الوقت المتطلب للقراءة 9 دقيقة
As a result of the operations that are performed in the centers with experience, this risk is less than 1%.
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What does my sex life look like after a liver transplant?
الوقت المتطلب للقراءة 9 دقيقة
There is no change.
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Can I have a baby after a liver transplant?
الوقت المتطلب للقراءة 9 دقيقة
There is no change.
Yes. Although it does not pose any obstacle for male donors, it is recommended that female donors wait one year before becoming pregnant.
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How long after liver transplant surgery will the recipient be discharged from the hospital?
الوقت المتطلب للقراءة 9 دقيقة
After an average of 15-20 days, this period can take up to a month.
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What can I eat and drink after a liver transplant?
الوقت المتطلب للقراءة 9 دقيقة
After surgery, you may eat and drink as soon as your intestines start working. If your gas outlets are provided, it’s okay to drink water. If you do not experience nausea or vomiting while drinking the water, you can eat liquids and soft foods. You can start eating normal food within two days. Sometimes, donors may not return to their eating habits so quickly, and some donors may experience severe nausea that lasts 3 to 4 days between 3-7 days after surgery. The less painkillers are used, the faster the bowel will recover.
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How often will I attend the examination after liver transplantation, liver transplantation in Turkey?
الوقت المتطلب للقراءة 9 دقيقة
Patients who complete the first 3 months, weekly and 15 days outpatients without any problems after transplantation, are called for monthly controls after the sixth month, every two months, and cases that have completed one year are called for observation every 3 months.
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What are the potential complications of donor liver transplant surgery?
الوقت المتطلب للقراءة 9 دقيقة
The risk of losing life in donor surgery is 0.2 – 0.5 percent, which is very low. Complications such as excess fat in the liver, anatomical dissection, unexpected formation, disparity in the liver or visible lumps in the abdomen, etc., which may occur during donor surgery, may cause this surgery to end. Post-operative bleeding and bile leakage may occur. This condition rarely requires a blood transfusion and repeat surgery. Although the incidence of these complications is very low for Liver Transplant in Turkey, there is always a risk. These risks will be explained to you in detail during the assessments. Small bile leaks, minor wound infections, and some gastrointestinal disturbances (constipation, indigestion, and nausea) are among the most common complications.
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Will I have severe pain after the surgery for a liver transplant?
الوقت المتطلب للقراءة 9 دقيقة
After the operation, pain is controlled by taking intravenous medications for the first 3 days and then orally.
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Will I live a normal life after liver transplant surgery in Turkey?
الوقت المتطلب للقراءة 9 دقيقة
If there are no complications, we expect you to return to your old life in about 3 months. The risk of long-term complications is very low.
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When can I travel after a liver transplant in Turkey?
الوقت المتطلب للقراءة 9 دقيقة
Don’t make any plans to travel abroad for at least 4 weeks, or preferably 8 to 12 weeks. If you want to go home and there is a doctor in your city who can go to the controls and has knowledge of liver transplantation from a living donor, you can go home after 2 to 4 weeks If you feel comfortable we must remind you that you will be called back to our center for evaluation and treatment in case The slightest suspicion of complications. At the end of the twelfth week, you can travel wherever you want.
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What is the cost of a liver transplant?
الوقت المتطلب للقراءة 9 دقيقة
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What is the success rate of liver transplantation?
الوقت المتطلب للقراءة 9 دقيقة
The success rate of liver transplantation depends on taking all necessary measures and conducting required tests before the procedure, as well as the medical team’s expertise and the technological advancements that contribute to the success of the transplant.
The success rate also relies on post-transplant care, thorough follow-up, and adherence to all instructions provided after the procedure.